Juvenile nasopharyngeal angiofibromas (JNA) are a rare benign but locally aggressive vascular tumor. Epidemiology Juvenile nasopharyngeal angiofibromas. Introduction: Juvenile nasopharyngeal angiofibroma (NAJ) is a tumor with .. Acessos Cirúrgicos no Angiofibroma Nasofaríngeo Juvenil – Relato de caso e. Juvenile nasopharyngeal angiofibroma (JNA) is a rare and benign but locally aggressive fibrovascular tumor arising from the posterolateral wall of the.

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Endoscopic resection of JNA, alone or in combination with limited external approaches, is the treatment of choice for JNA in early stages; in certain centres with sufficient experience, JNA in advanced stages are also intervened. Genetic evidence for an androgen-dependent tumor?

Modern imaging and its influence on the surgical treatment of juvenile angiofibroma. Salvage Surgery in the Treatment of Local Recurrences of Head Neck, 19pp.

It shows very aggressive behavior due to local invasiveness and is associated with various symptoms. The surgical management of extensive nasopharyngeal angiofibromas with the infratemporal fossa approach.

Surgery is the treatment of choice for JNA. Spontaneus regression of juvenile nasopharyngeal angiofibroma. Squamous-cell carcinoma Adenocarcinoma Mucinous cystadenocarcinoma Large-cell lung carcinoma Rhabdoid carcinoma Sarcomatoid carcinoma Carcinoid Salivary gland—like carcinoma Adenosquamous carcinoma Papillary adenocarcinoma Giant-cell carcinoma.

Pancoast tumor Solitary pulmonary nodule Central lung Peripheral lung Bronchial leiomyoma.

We also quantified mean blood loss during surgery and transfusion requirements. Eur J Gen Med. Arch Otolaryngol Head Neck Surg,pp. Introduction Nasopharyngeal angiofibroma juveinl a histologically and biologically benign tumor with aggressive behavior due to its location and associated symptoms including significant epistaxis and nasal obstruction The tumor invades the infratemporal fossa or orbit without intracranial involvement.


CT is particularly useful at delineating bony changes. Nasal cavity Esthesioneuroblastoma Nasopharynx Nasopharyngeal carcinoma Nasopharyngeal angiofibroma Larynx Laryngeal cancer Laryngeal papillomatosis. Int J Pediatr Otorhinolaryngol. The first description of an endoscopic resection was published in Electron dense granules composed of tightly bound RNA protein complexes Stromal cells are myofibroblasts. Professionals Review article English Clinical practice guidelines English Endoscopic Ressection of Juvenile Angiofibroma.

Articles Cases Courses Quiz. Severe haemorrhage constitutes a high risk in JNA and its surgical management could be complex. Postoperative radiotherapy was used to treat 3 patients, with 2 of them having stable tumours at present and another being disease-free.

The exact site of origin is contentious as these masses usually present when they have reached considerable size. Some surgeons, however, do not routinely perform embolization preoperatively, finding that embolization is justified only in larger tumors Summary and related texts.

Juvenile nasopharyngeal angiofibroma

Avid enhancement is noted on contrast-enhanced CT. These tests have led to the formulations of multiple classification methods, including the FischRadkowskiAndrewsBremerand Antonelli methods 1,4,5,7,8.

The mean time from onset of symptoms until surgery was 12 and half months 1—60 months. We reviewed the surgical registry of the Otolaryngology Service at our hospital from until Maycollecting data from medical records pertaining to patients diagnosed with JNA.

Nasopharyngeal angiofibroma: our experience and literature review

J Laryngol Otol,pp. Many studies highlight the benefit of preoperative arterial embolization to control bleeding intraoperative 16,29, Lastly, if the involvement of the anterior fossa or planum sphenoidale is very broad or intradural, a craniofacial or subcranial approach with acceptable morbidity can be used.


The purpose of this study is to present our experience in the treatment of JNA, primarily angiofibtoma on the type of surgical approach used, and to review the disease based on the literature and our own experience. Mean patient age was 16 years old.

Vascularization arises most frequently from the maxillary artery i. Anterior bowing of the posterior maxillary wall, due to invasion of the pterygomaxillary space on axial CT, known as the Holman-Miller sign is one of the characteristic findings. Case 2 Case 2.

Angiofibroma nasofaríngeo juvenil – Wikipedia, la enciclopedia libre

Given the short period of patient follow-up, there were anguofibroma two relapses in two years. Given the short period of patient follow-up, there were only two relapses in one year. Axial section in computed tomography demonstrating obliteration of the nasal cavity and maxillary sinus.

A higher density toward the periphery is noted, which was seen in the present case too.

The third patient with a Fisch I tumor underwent surgery with embolization, but without clamping of the external carotid arteries. Transoral “adenoidectomy” excision of juvenile nasopharyngeal angiofibromas. The tumor invades the nasal sinuses or the pterygomaxillary fossa with bone destruction.

However, most authors agree that JNAs arise from the posterior choanal tissues in the region of the sphenopalatine foramen.