Virchow-Robin (VR) spaces surround the walls of vessels as they course from the subarachnoid space through the brain parenchyma. English Translation, Synonyms, Definitions and Usage Examples of Spanish Word ‘espacio de Virchow-Robin’. Otros sugieren compromiso con dilatación de los espacios de Virchow-Robin, desmielinización difusa con pérdida de células gliales y axonopatía que deriva.

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Perivascular spacesalso known as Virchow-Robin spacesare pial-lined interstitial fluid-filled spaces in the brain that surround perforating vessels. They do not have a direct connection with the subarachnoid space and in fact, the fluid within them is a slightly different composition as compared to CSF.

On axial imaging, they appear as smoothly demarcated fluid-filled cysts, typically less than 5 mm in diameter, vircgow the same attenuation or intensity as CSF, and often found in the basal ganglia or midbrain. When perivascular spaces are very large, they are referred to as tumefactive perivascular spaces.

When located in the anterior temporal lobe and related to a vascular loop, they robim known as anterior temporal lobe perivascular spaces ; however, these likely represent a different entity compared to typical scattered perivascular spaces.

Perivascular spaces are very common, and increasingly seen with better MRI image resolution. They are almost invariably asymptomatic, even when quite large. Perivascular spaces are normal structures which consist of a single or double layer of invaginated pia surrounding small cerebral blood vessels 8, Perivascular spaces which are visible on imaging are typically esapcio than 5 mm in diameter, but can reach much larger sizes.



Perivascular space

A so-called “giant” perivascular space or tumefactive perivascular spaceand can exert enough mass effect to be symptomatic 1. They tend to enlarge with age and hypertension. Previously, perivascular spaces were believed to be entirely incidental findings, mostly significant so as not to be mistaken for a more sinister pathology. This is especially true with a tumefactive or unusual in appearance e.

This is related to the observation that, although a few scattered perivascular spaces are a nearly xe imaging finding, the number and prominence of these spaces increases with aging and along with other findings of microvascular disease, e.

Perivascular space – Wikipedia

The association remains controversial Most commonly, perivascular spaces are located in the lower half of the basal gangliaespecially in the anterior perforated substance along the line of sepacio anterior commissure 3. They are also found in The cortical regions are spared.

In contrast to lacunar infarcts encountered more frequently in the upper half of the putamen, perivascular spaces are seen more often in the lower half. A special type of perivascular space occurs in the anterior temporal lobe and can mimic a cystic tumor. These are discussed separately: As they are filled with a fluid similar to CSF, perivascular spaces have appearances akin to water on all imaging modalities and sequences.

Differentiating them from foci of encephalomalacia that result from chronic lacunar infarcts can be challenging but is important as imaging findings of ischemia can lead to patients being put on medication such as antiplatelet therapy.


They follow CSF signal on all pulse sequences 7. Although generally cyst-like on axial sequences, on sagittal and coronal sequences a linear radiating morphology may be seen consistent with their role in surrounding vessels. In a minority of cases, especially when they are large, a thin increased T2-signal halo may be seen.

Usually, they will have a positive mass effect. On T2 sequences, a traversing vessel is sometimes seen. To quiz yourself on this article, log in to see multiple choice questions. You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Unable to process the form. Check for errors and try rovin. Thank you for updating your details. Log in Sign up.

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Cases and figures Imaging differential diagnosis. Giant tumefactive perivascular spaces. Edit article Share article View revision history. Synonyms or Alternate Spellings: Support Radiopaedia and see fewer ads.

Case 4 Case 4. Case 5 Case 5. Case 6 Case 6. Case 7 Case 7. Case 8 Case 8. Case 12 Case Case 14 Case Firchow fissure cyst Choroid fissure cyst. Lacunar infarct Lacunar infarct. Loading Stack – 0 images remaining.